United States · Retail pharmacy · Brand-name

Costco Member Prescription Program review

Brand-name Wegovy or Ozempic at $349/month self-pay through Costco Pharmacy, with the clinical side run by Sesame from $59/month.

Reviewed 2026-08-178/13 checklist items publishedProvider site ↗

Overview

This is two things sold together. The medicine comes from Costco Pharmacy at a self-pay price, and the prescribing comes from Sesame, the clinician marketplace reviewed separately on this site. Sesame describes Wegovy and Ozempic injections at Costco Pharmacy as “$349 per month (50% off the traditional price)” for members self-paying, and the Wegovy pill at “as little as $149 per month”.

The clinical wrapper is Success by Sesame, “as low as $59/mo. with an annual subscription”, which covers “video consults with a licensed clinician, labs, messaging, access to prescriptions for weight loss medications, and ongoing care.” Members already enrolled in the earlier Costco weight-loss programme continue at “$179 every 3 months” with benefits unchanged.

Everything here is brand-name and FDA-approved — Wegovy, Ozempic, Zepbound, Mounjaro and Rybelsus are the medications named. That makes this one of the few routes on this site where the cheap column and the approved column are the same column. The catch is the Costco membership, which you must hold and which costs money the price above does not include.

Medications and supply

Brand-name only, dispensed by Costco Pharmacy. No compounded product is involved, so none of the compounding caveats elsewhere on this site apply — and neither does the litigation risk hanging over the compounded tier.

  • Wegovy (semaglutide) injection and pill
  • Ozempic (semaglutide)
  • Zepbound (tirzepatide)
  • Mounjaro (tirzepatide)
  • Rybelsus (oral semaglutide, type 2 diabetes)

How the service works

Consultation
Through Sesame: video consults with a licensed clinician, included in the Success by Sesame subscription.
Eligibility
Not stated in the sources we checked.
Provider involvement
Licensed clinicians via the Sesame marketplace, with messaging and ongoing care included in the subscription.
Lab requirements
Labs are included in the Success by Sesame subscription.
Pharmacy fulfilment
Costco Pharmacy.
Shipping
Not stated in the sources we checked.
Support services
Messaging and ongoing care included in the subscription.

What it costs

Published prices for Costco Member Prescription Program
ItemPublished priceNotes
Wegovy or Ozempic injection$349 / monthSelf-pay at Costco Pharmacy, described as 50% off the traditional price
Wegovy pillfrom $149 / monthMatches Novo’s own self-pay price for the titration doses
Success by Sesamefrom $59 / monthWith an annual subscription — clinician visits, labs, messaging and ongoing care
Existing Costco weight-loss enrollees$179 / 3 monthsGrandfathered, benefits unchanged
Costco membershipNot includedRequired to access any of the above
Membership fee
A Costco membership is required and is not included in any of the prices above. The Sesame subscription is a second, separate fee.
Medication fee
Charged separately from the Sesame subscription — the $59 does not include the drug.
Insurance
The $349 is a self-pay price. Insurance is not part of this route, which is what makes it comparable with the cash prices elsewhere on this site.
HSA / FSA
Not stated in the sources we checked.
Cancellation
Not stated in the sources we checked.
Refunds
Not stated in the sources we checked.

Pros

  • Brand-name, FDA-approved medication at a cash price competitive with much of the compounded tier — a combination almost nothing else here offers.
  • No exposure to the compounding litigation or the 503B bulks-list proposal, because nothing is compounded.
  • Labs and clinician visits are bundled into the Sesame subscription rather than billed separately.
  • Carries the Wegovy pill at $149, matching Novo’s own direct price.
  • Existing enrollees were grandfathered rather than repriced.

Cons

  • Three costs stack: Costco membership, the Sesame subscription and the medication.
  • The $349 is for the two semaglutide injections. Prices for Zepbound and Mounjaro are not stated in the material we could retrieve.
  • No cancellation or refund terms published for the bundle.
  • The $149 pill price, like Novo’s own, covers titration doses rather than the 25 mg maintenance dose.
  • Requires a paid warehouse membership to access healthcare pricing at all, which is a strange gate to put on a prescription.

Who it may suit

Anyone who already holds a Costco membership and wants brand-name semaglutide without insurance. At $349 for the real thing, the argument for a compounded copy gets considerably weaker — and this route cannot be enjoined out from under you.

Limitations

  • costco.com timed out on direct retrieval, so the pricing here comes from Sesame’s own announcement of the partnership rather than from Costco’s page.
  • Prices for Zepbound and Mounjaro through this route are not stated in the material we could reach.
  • No published eligibility criteria, cancellation or refund terms for the combined offer.

Questions

How much is Ozempic at Costco?

Sesame describes Wegovy and Ozempic injections at Costco Pharmacy as $349 a month for members self-paying, which it characterises as 50% off the traditional price. You need a Costco membership, and the clinical side is a separate Sesame subscription from $59 a month.

Is this compounded?

No. Every medication named here is brand-name and FDA-approved — Wegovy, Ozempic, Zepbound, Mounjaro and Rybelsus. That means none of the compounding caveats on this site apply to it, and neither does the manufacturer litigation or the 503B bulks-list proposal.

What does the $59 Sesame subscription cover?

Video consults with a licensed clinician, labs, messaging, access to prescriptions and ongoing care — at the annual-subscription rate. It does not cover the medication, which is charged separately at the pharmacy.

Do I need a Costco membership?

Yes, and it is not included in any of the quoted prices. Factor it in before comparing $349 against a telehealth service with no membership gate.

Is it cheaper than compounded?

Not always on the sticker, but the comparison is not like for like. $349 buys an FDA-approved product from a named retail pharmacy that no court can enjoin. Several compounded routes here are cheaper per month and carry supply risk the manufacturers are actively litigating.

Sources

Everything on this page traces to one of the links below, retrieved on the date shown. Prices and programme terms in this market change without notice — confirm against the provider before you buy.

  1. 01Costco — Member Prescription Program (direct retrieval timed out; listed for reference)retrieved 2026-08-17
  2. 02Sesame — “Costco Weight Loss Program: Latest Status, Pricing & More”, the partner’s own announcement of the pricing quoted hereretrieved 2026-08-17